A Comprehensive Review on Extraction, Structure, Detection, Bioactivity, and Metabolism of Flavonoids from Sea Buckthorn (Hippophae rhamnoides L.)

Sea buckthorn (Hippophae rhamnoides L.) is an important plant with homology of medicine and food. It has rich nutritional medicinal properties. used as a traditional Chinese therapeutic functions invigorating spleen, relieving cough, eliminating food, phlegm, dispersing blood stasis, promoting circulation. This review comprehensively summarized flavonoids from sea L.), including extraction methods (solvent extraction, ultrasound-assisted microwave-assisted enzyme-assisted collaborative extraction), two structure types (18 flavone aglycones 81 glycosides), detection (UV, HPLC, NMR), bioactivities (antiviral, anti-inflammatory, hepatoprotective, weight-reducing, hypoglycemic activities), physiological metabolisms (most are converted into small molecule monophenolic acids through intestinal microbial catabolism). will supply theoretical basis valuable reference for researching exploiting in the future. Practical Applications. edible medical many functional A comprehensive on structure, detection, bioactivity, metabolism was made this paper. provide foundation further studies focusing its development utilization.